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Accutane, intended indicated for the treatment of severe, recalcitrant, nodular acne, has been linked with several serious side effects, including serious birth defects and suicide. Accutane, or Isotretinoin, is a retinoid that is related to retinoic acid and retinol, or Vitamin A. Isotretinoin inhibits sebaceous gland function and keratinization. Accutane treatment for 15 to 20 weeks results in complete and prolonged remission of acne is most patients. Sometimes, a second course of treatment is needed.

In addition to birth defects and suicide, Parker Waichman Alonso Mark LLP is investigating Accutane cases involving inflammatory bowel disease, crohn’s disease, colitis, loss of vision, loss of hearing and growth disc problems. If you or a loved one has been injured by Accuntane please complete the case inquiry form on the right side of this page for a free evaluation.

#1 2002-04-17 04:43:00

kelly s
Member
From: Illinois
Registered: 2002-04-16
Posts: 1

Accutane depression

I'm just wondering if anyone else out there experienced the behavior that I did while on Accutane.  My grades and golf scores went down the toilet and I engaged in very self-destructive behaviors.  Does anyone else have a similar experience?

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#2 2002-10-16 17:57:00

KeepNup
Member
From: Angela
Registered: 2002-10-15
Posts: 1

Re: Accutane depression

I don't play golf or go to school.  My experience, is one of cyclic severe depression.  I'm convinced accutane really screwed up the way my brain chemistry reacts to hormonal changes. 

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#3 2003-01-06 06:42:00

kr625
Member
Registered: 2003-01-05
Posts: 1

Re: Accutane depression

I was 25 when a dermatologist first prescribed Accutane. I had been breaking out moderately to severely from age 12. While taking Accutane, I experienced no serious ill effects, other than the usual dry skin, lips, etc. As a matter of fact, I never felt and looked better! Especially when I saw the rapid improvement in my skin.
Now, 4 years later, I have not had one breakout and people often remark on how nice my skin is.
I think accutane is a miracle drug. I feel great sympathy for people who have not had a positive experience while on it.
I am wondering though, if the depression side effects are related to the age of the person on the drug? Like I said, I was a grown woman when I first started to take it.


<font size=-1>[ This Message was edited by: kr625 on 2003-01-06 09:42 ]</font>

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#4 2003-01-22 16:35:00

auto_eng
Member
Registered: 2003-01-21
Posts: 1

Re: Accutane depression

I struggled with really really bad skin during puberty. I was on this drug for about 18 months which I think is a faily long time in comparison to others. I had the usual side effects (dry skin ect) but don't feel I suffered much in the way of depression or modified behavior. Taking into account I was on it at the age of 17 so depession and abnormal behaviour can just be a part of growing up and wouldn't really stand out anyway.
Any depression I felt was outweighed by the comfort of having clear skin. Sorry to hear that other do not feel the drug was a positive thing for them.

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#5 2003-03-11 15:04:00

puddycat
Member
Registered: 2003-03-10
Posts: 12

Re: Accutane depression

Unfortunately my son almost took his life due to the depression brought on using Accutane.  Luckily I found the note he wrote and we went immediately into therapy.  After 1 1/2 years he is doing better and understanding how depression brought him to that terrible point.
p.s. Yes he also had dry lips, etc.


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#6 2003-07-02 12:37:11

cpellett
Member
Registered: 2003-05-13
Posts: 2

Re: Accutane depression

i am glad that some people have not experience any ill side effects while on accutane.  but i was one of the many unlucky ones out there.  not only did i have extremely dry lips to the point of blistering all around my mouth, but i became extremely depressed, neglected my house and my kids, i went from a 4.0 to making F's in school and had to drop out of nursing school.   i also begin engaging in extremely self-destructive behaviors.   i am very ashamed of my behavior now that i have my mind back.  but i suffered all that for nothing!  within about 10 months, my cyctic acne came back!  and it came back with a vengeance! so the past 6 years after taking accutane, i am still fighting this ailment with all sorts of antibiotics, creams, etc. i want my money back, plus compensation for all the pain and suffering my family and i had to go through.

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#7 2003-08-10 06:12:13

Miguel Legaspi
Member
From: san diego, California
Registered: 2003-08-10
Posts: 1

Re: Accutane depression

I was 25 years old when FIRST perscribed Acutane, it was for severe Acne on my back. I was in the Military stationed in Monterey, CA. I was a stelar performer and had a VERY prommising career, Never been reprimended at all, was on the fast track of the promotion ladder. I went to see a Civilian Dr. out of pocket for the military did not help with severe forms of skin disorders, It was sugested I go, At first it was dry skin, lips, bla bla, bla............. for 4-5 months, I started suffering from SEVERE head aches and was advised by my doctor to discontine the medication imediatley, and DO NOT use it again. All was well after that. in 1997 I was transfered to Diego Garcia in the Indian Ocean, I started becoming very depressed, I really liked the isolated duty but the depression was overwhelming, suicidal at times. I was medivaced to a military hospital and found unfit for overseas duty.  I did love the military lifestyle but left it after 10 years and 6 levels of rank, only to go into another branch and accept only 2 levels of rank after completion of recruit training, all this at 28 years old, this was not easy, all my peers were 18 years of age. I left the Navy only to join the Marine Corps. I was allways depressed during this time of my life, taking chances, after serving 8 years in this branch of the service I became so depressed that I found myself wanting to atempt to hurt myself with a weapon. I was once again placed in a hospital,  I was found disabled, and retired from my career, at 18 years. The Veterans Administration found me 100% disabled and totally unemployable, Social Security agreed. My depresion worsend over time and I found myself heavely medicated at times unable to deal with anything at all, I was evaluated by social security and found very qualified as well due to this disability called depresion, I am still taking medication and only able to do meneal simple jobs but not for an extended period of time. Life is hard now at 41, I try yo make due as best I can, I often wonder if I would not have lost my career if I had not taken this medication called Acutane, I was once a proud man and a great defender, you see, I was a Marine!

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#8 2004-03-03 12:43:15

xdebater
Member
From: Austin/houston
Registered: 2004-03-03
Posts: 1

Re: Accutane depression

I can understand most of your complaints, however where is the link?

How do you guys know for sure that Accutane had caused your illness?

I underwent the use of accutane at the age of 16, I at the time was unaware of the fact that it was an anti-depressant.  I felt that I was misguided by my parents who were aware of its full use.  I have had suicidal thoughts, and a feeling of deppression ever sense the use of the drug.  However I have no actual, physical link to the fact that it was the medicine and not my own life causing these feelings.  I can definitely understand that some of the ones that have commited suicide should feel some remorse towards accutane, however where is the will power?  Where were the parents to notice these things?  I dont see how you can blaim accutane at the point in time in which you realize that you are having adverse effects and you knew about the warnings pre hand to taking the drug. 

I can see your points if you didnt know that accutane had side affects such as these but at the point in time you knew about them, how can you blaim the drug?


Peace may lay in the soul that doesnt speak.

Speak Louder.

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#9 2004-06-29 06:32:06

vootas
Member
Registered: 2004-06-29
Posts: 1

Re: Accutane depression

Why does everybody instantly blame accutane for their depression? There are hundreds of different causes of depression in teenagers and young adults, people need to take responsibilty for their actions and not go blaming Accutane at the drop of a hat.
Although I do agree that the side effects of the drug need to be investigated further, and do feel sympathy for those who have suffered the rarer side affects of the drug (eg. Ulcerative Colitis), the people who are calling for the drug to be pulled from the market do not realise what positive life changing effects the drug has had on millions of people all over the world. I am on my 3rd month of Roaccutane treatment, and my face has improved out of sight. My friends say that I look so much happer since i started my treatment, and my unversity marks have improved because I feel more confident and I no longer stay inside because my acne was 'too bad'. If your class action was to succeed, and Accutane was forced from the market, you litigious american bastards will have denied millions the right to have a clear face. Think of the people (like I was) that were too scared to leave the house because they looked like a freak, who were too scared to talk to people because they knew that others would just stare at their face.
As for the pregnancy issue, all you have to do is use two forms of contraception. There is no way that somebody should be able to sue because they fall pregnant, given the amount of warning on the packets and the avalibility of reliable contraception.
I wish you all the best with your problems, and urge you to consider the implications of a law suit against accutane.

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#10 2004-06-29 09:36:31

serveman
Member
Registered: 2004-06-29
Posts: 2

Re: Accutane depression

Vootas, you speak with a blind ignorance regarding the drug and why people want it off the market. It has been proven that it causes depression, I didn't immediately blame the drug, in fact didn't even think about accutane for 10 years after taking it. I was just as you are right now, happy to have such a clear face. But right now, I would go back and not take it because it has SEVERELY altered my future. I had my neck looked at recently due to pain and the doctor was in shock. I had spurring and degradation of my spine that he can not explain. I was hopitalized with Thrush and esophogitis for 7 days without being able to eat or drink and was tested for aids due to a "Immune Deficiency" that again was unexplained in a 29 year old healthy male. Looking back at my college years with my wife whom I have been with over 10 years now, we see what Accutane did to me. We passed off extremely aggressive and angry behavior of mine as stress related to school and tests. I was out of control and a 4.0 college student....I didn't make sense. I, for the only time in my life sat time and time again with the desire to die and make the "noise" in my head go away. I was told dry lips, nose bleeds, and headaches...and got all those, what I wasn't told is that I may kill myself, degrade all my organs and bones, and live a much more painfull life at age 30 with 3 young children that I would love to grow up with and be playing sports with in my 40's. I was told this won't happen with the condition of my neck. 10 years ago, they didn't know this of the drug, now they do and people like you spout curse words to those of us trying to stop the money grubbing drug companies from destroying lives.

If asked the following, how would you respond.

I can give you a clear face, but you may die or be physically handicapped with that clear face...Do you want this drug or to try a different one?

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#11 2005-10-06 10:28:25

parcel806
Member
Registered: 2005-10-06
Posts: 3
Website

Re: Accutane depression

[quote]Vootas, you speak with a blind ignorance regarding the drug and why people want it off the market. It has been proven that it causes depression, I didn't immediately blame the drug, in fact didn't even think about accutane for 10 years after taking it. I was just as you are right now, happy to have such a clear face. But right now, I would go back and not take it because it has SEVERELY altered my future. I had my neck looked at recently due to pain and the doctor was in shock. I had spurring and degradation of my spine that he can not explain. I was hopitalized with Thrush and esophogitis for 7 days without being able to eat or drink and was tested for aids due to a "Immune Deficiency" that again was unexplained in a 29 year old healthy male. Looking back at my college years with my wife whom I have been with over 10 years now, we see what Accutane did to me. We passed off extremely aggressive and angry behavior of mine as stress related to school and tests. I was out of control and a 4.0 college student....I didn't make sense. I, for the only time in my life sat time and time again with the desire to die and make the "noise" in my head go away. I was told dry lips, nose bleeds, and headaches...and got all those, what I wasn't told is that I may kill myself, degrade all my organs and bones, and live a much more painfull life at age 30 with 3 young children that I would love to grow up with and be playing sports with in my 40's. I was told this won't happen with the condition of my neck. 10 years ago, they didn't know this of the drug, now they do and people like you spout curse words to those of us trying to stop the money grubbing drug companies from destroying lives.[/quote]

Ahh woops, now i get it.


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