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Has anyone out there had an experience with Xeloda?  My mother was placed on Xeloda about seven years into her eight year battle with breast cancer.  It seems that this was the start of the end.  No one ever told us that  Xeloda can cause kidney problems and that we needed to watch out for signs of dehydratation.  Last fall, for days, my mother seemed so lethargic and then even disoriented.  She had also experienced jerking motions (not voluntary) of her hands and arms.  She kept dropping things.  I guess we though it was the cancer progressing.  We didn't know what to think.  Finally, we just took her to the emergency room at the hospital and they admitted her.  They did all sorts of tests, and then diagnosed her as being terribly dehydrated and suffering from kidney dysfunction.  She never previously had anything wrong with her kidneys.  She had no recall of her first few days in the hospital and had even been making really weird statements.  The worst part was that this began her total downfall.  We lost her several months later, in January of this year.  But now I'm angry.  I imagine this episode didn't change the outcome, but she didn't need to suffer like that.  She never recovered from the kidney problem and just got weaker and weaker.  Has anyone ever heard of this?