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Astra Zeneca’s popular schizophrenia drug Seroquel has been linked with a high incidence of diabetes, hyperglycemia and other blood sugar disorders. Seroquel is in the class of drugs called atypical antipsychotics, which are a newer class of antipsychotics touted as having a lower incidence of blood sugar disorders than the older medications such as Haldol and Thorazine. Seroquel was approved by the FDA in 1997.

Data from a study that was reported at a conference of the International Society for Pharmacoepidemiology in Philadelphia August 23 and 24, 2003 showed that patients on Seroquel had 3.34 times as many cases of diabetes as those on older antipsychotic drugs. The study of 19,878 U.S. military veterans between October 1998 and October 2001 indicated that Seroquel and other members of the new class of anti-psychotic drugs posed a higher risk of diabetes. The effect was most pronounced with Seroquel.

If you or a loved one was injured by Seroquel, please complete the free case inquiry form on the right side of this page.

#1 2006-02-07 09:14:53

Melanie27
Member
Registered: 2006-02-07
Posts: 1

The Liver & Seroquel?

My Husband had Hepatitis C was put on seroquel in 2004 & that year went threw chemo for HCV It put it into remission but after feeling horrable still they reran blood work which showed his liver enzymes still high the Dr ran more test & found on top of the Fibrosis in his liver he also has Severe fattly liver now a year latter there wanting another biopsi because of possable chirosis & hardening of the liver the recently ran blood work & his fasting gluclose was high his Triglisterides,Cholesterol ,AST,ALTMCV,MCH,EOSINOPHILS were all high his white  bloodcount was low & so is is platelet count. & on top of all this he has had Asthma kick in & severe headaches & Dm type 2 has all this just been a coincidence that it all started after taking seroquel or is it possable its all caused from it.Im just worried that it's causing his liver to get worser all the time his dr has known seroquel could cause this & told him it was took off the market in europe but hasnt took him off it yet because it helps his mania from his bipolar whats more important my hubbys life or his bipolar disorder .

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#2 2006-11-27 22:50:43

haroldb
Member
Registered: 2006-11-27
Posts: 27

Re: The Liver & Seroquel?

I would suggest you go the Medline web site and put in key words relating to your problem.  You should be able to find abstracts to articles which can help you:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed

Good luck, Harold Boxenbaum, Ph.D.    www.arishel.com

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#3 2007-02-17 17:59:18

Kevin9254
Member
Registered: 2006-11-24
Posts: 5

Re: The Liver & Seroquel?

I used seroquel and the drug induced diabetes and hyperglycemia.  It(the diabetes) in turn, caused NASH(non-alcoholic steatohepatitis) and second stage NAFLD(non alcohlic fatty liver disease).  Can be verified by copy of liver biopsy.

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#4 2007-02-21 16:24:25

Kevin9254
Member
Registered: 2006-11-24
Posts: 5

Re: The Liver & Seroquel?

see www.pulaskilawfirm.com regarding "Researchers reported 3 cases of severe liver problems from seroquel and one death."

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